3D bioactive composite scaffolds for bone tissue engineering
نویسندگان
چکیده
منابع مشابه
Bioactive Glass Scaffolds for Bone Tissue Engineering
In materials science, the ability to develop porous constructs with high mechanical strength is important for a broad range of emerging applications, including filters, catalyst support, and tissue engineering scaffolds. Particularly for orthopedic surgery, the regeneration of large bone defects in load-bearing limbs remains a challenging problem that require scaffolds that combine the strength...
متن کاملComposite Scaffolds for Bone Tissue Engineering
Biomaterial and scaffold development underpins the advancement of tissue engineering. Traditional scaffolds based on biodegradable polymers such as poly(lactic acid) and poly(lactic acidco-glycolic acid) are weak and non-osteoconductive. For bone tissue engineering, polymer-based composite scaffolds containing bioceramics such as hydroxyapatite can be produced and used. The bioceramics can be e...
متن کاملFabrication of Porous Hydroxyapatite-Gelatin Composite Scaffolds for Bone Tissue Engineering
Background: engineering new bone tissue with cells and a synthetic extracellular matrix represents a new approach for the regeneration of mineralized tissues compared with the transplantation of bone (autografts or allografts). Methods: in this study, to mimic the mineral and organic component of natural bone, hydroxapatite (HA) and gelatin (GEL) composite scaffolds were prepared. The raw mater...
متن کاملAligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
متن کاملBioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering
Traditionally, bioactive glasses have been used to fill and restore bone defects. More recently, this category of biomaterials has become an emerging research field for bone tissue engineering applications. Here, we review and discuss current knowledge on porous bone tissue engineering scaffolds on the basis of melt-derived bioactive silicate glass compositions and relevant composite structures...
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ژورنال
عنوان ژورنال: Bioactive Materials
سال: 2018
ISSN: 2452-199X
DOI: 10.1016/j.bioactmat.2017.10.001